Non-native Aggregation of Alpha-chymotrypsinogen A from a Combined Experimental and Modeling Approach

Non-native Aggregation of Alpha-chymotrypsinogen A from a Combined Experimental and Modeling Approach

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The LENP model was successfully applied to determine details of the aCgn aggregation mechanism. The combined modeling and experimental approach developed and employed in this thesis is expected to be of general utility in interpreting aggregation behaviors for a broad range of experimental systems beyond alpha-chymotrypsinogen.under type II conditions (open circles) are due to the fact that ss was calculated from Eq 3.27 for m = 0.001, while the symbols are for t/t50 = 4. Therefore, the corresponding m values are slightly higher than 0.001. The differences between theanbsp;...


Title:Non-native Aggregation of Alpha-chymotrypsinogen A from a Combined Experimental and Modeling Approach
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Publisher:ProQuest - 2008
ISBN-13:

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